In Vitro Reference Models for Multi-Layer Tissue Structures (MULTIS)

This site contains data to understand the mechanics of multi-layer tissue structures of the limbs, particularly of the lower and upper legs and arms. Anatomical and mechanical data were collected on extremities of 9 adult subjects (5 male, 4 female) from the general population. An ultrasound system was instrumented with a load transducer for in vitro characterization of skin, fat, and muscle thicknesses in the extremities at unloaded and loaded (indentation) states. The unloaded state provided anatomic measures of the tissue layers for 48 regions, while the loaded state provided the tissue mechanical response in 8 regions. Additionally, computed tomography (CT) and magnetic resonance (MR) imaging was performed on each. All imaging sets and relevant segmentations were included. Further details of the analysis can be found in the publication “Reference data on in vitro anatomy and mechanics of tissue layers of musculoskeletal extremities ” by Schimmoeller, et al.

This data was collected under the research and development project titled “Reference Models for Multi-Layer Tissue Structures" conducted by the Cleveland Clinic Foundation and made possible by a contract vehicle which was awarded and administered by the U.S. Army Medical Research & Materiel Command under award number: W81XWH-15-1-0232. The views, opinions and/or findings contained in this website are those of the authors and do not necessarily reflect the views of the Department of Defense and should not be construed as an official DoD/Army position, policy or decision unless so designated by other documentation. No official endorsement should be made.

This data is made available under a Creative Commons Attribution 4.0 International License (see license.txt for more information).